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An experiment in bovine genetic modification goes horrifically wrong in writer/director Billy O’Brien’s debut feature, Isolation. John Lynch stars as Dan a cattle farmer on the remote Irish countryside, whose ex, Orla (Essie Davis of the Matrix films), a veterinarian, has convinced him to take part in a profit-driven experiment on his cows, run by John (Marcel Iures), an officious scientist who seems very concerned with maintaining secrecy.